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GASTRIC CANCER SUSCEPTIBILITY AFTER H. PYLORI INFECTION

MedGen UID:
864667
•Concept ID:
C4016230
•
Finding
OMIM®: 147679; 147720

Professional guidelines

PubMed

Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).
Homan M, Jones NL, Bontems P, Carroll MW, Czinn SJ, Gold BD, Goodman K, Harris PR, Jerris R, Kalach N, Kori M, Megraud F, Rowland M, Tavares M; on behalf of ESPGHAN/NASPGHAN
J Pediatr Gastroenterol Nutr 2024 Sep;79(3):758-785. Epub 2024 Aug 15 doi: 10.1002/jpn3.12314. PMID: 39148213
Current paradigms in the management of refractory Helicobacter pylori infection.
Jearth V, Panigrahi MK
Indian J Gastroenterol 2023 Dec;42(6):766-779. Epub 2023 Sep 22 doi: 10.1007/s12664-023-01448-3. PMID: 37737326
Toward population specific and personalized treatment of Helicobacter pylori infection.
Liou JM, Chen PY, Kuo YT, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium
J Biomed Sci 2018 Oct 2;25(1):70. doi: 10.1186/s12929-018-0471-z. PMID: 30285834Free PMC Article

Recent clinical studies

Etiology

Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).
Homan M, Jones NL, Bontems P, Carroll MW, Czinn SJ, Gold BD, Goodman K, Harris PR, Jerris R, Kalach N, Kori M, Megraud F, Rowland M, Tavares M; on behalf of ESPGHAN/NASPGHAN
J Pediatr Gastroenterol Nutr 2024 Sep;79(3):758-785. Epub 2024 Aug 15 doi: 10.1002/jpn3.12314. PMID: 39148213
Molecular testing-guided therapy versus susceptibility testing-guided therapy in first-line and third-line Helicobacter pylori eradication: two multicentre, open-label, randomised controlled, non-inferiority trials.
Chen MJ, Chen PY, Fang YJ, Bair MJ, Chen CC, Chen CC, Yang TH, Lee JY, Yu CC, Kuo CC, Chiu MC, Chou CK, Chen CY, Hu WH, Tsai MH, Hsu YC, Shun CT, Luo JC, Lin JT, El-Omar EM, Wu MS, Liou JM; Taiwan Gastrointestinal Disease and Helicobacter Consortium
Lancet Gastroenterol Hepatol 2023 Jul;8(7):623-634. Epub 2023 May 10 doi: 10.1016/S2468-1253(23)00097-3. PMID: 37178702
High Effective of 14-Day High-Dose PPI- Bismuth-Containing Quadruple Therapy with Probiotics Supplement for Helicobacter Pylori Eradication: A Double Blinded-Randomized Placebo-Controlled Study.
Poonyam P, Chotivitayatarakorn P, Vilaichone RK
Asian Pac J Cancer Prev 2019 Sep 1;20(9):2859-2864. doi: 10.31557/APJCP.2019.20.9.2859. PMID: 31554388Free PMC Article
Epidemiology, clinical impacts and current clinical management of Helicobacter pylori infection.
Mitchell H, Katelaris P
Med J Aust 2016 Jun 6;204(10):376-80. doi: 10.5694/mja16.00104. PMID: 27256648
Helicobacter pylori infection in gastric cancerogenesis.
Konturek PC, Konturek SJ, Brzozowski T
J Physiol Pharmacol 2009 Sep;60(3):3-21. PMID: 19826177

Diagnosis

Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).
Homan M, Jones NL, Bontems P, Carroll MW, Czinn SJ, Gold BD, Goodman K, Harris PR, Jerris R, Kalach N, Kori M, Megraud F, Rowland M, Tavares M; on behalf of ESPGHAN/NASPGHAN
J Pediatr Gastroenterol Nutr 2024 Sep;79(3):758-785. Epub 2024 Aug 15 doi: 10.1002/jpn3.12314. PMID: 39148213
Molecular testing-guided therapy versus susceptibility testing-guided therapy in first-line and third-line Helicobacter pylori eradication: two multicentre, open-label, randomised controlled, non-inferiority trials.
Chen MJ, Chen PY, Fang YJ, Bair MJ, Chen CC, Chen CC, Yang TH, Lee JY, Yu CC, Kuo CC, Chiu MC, Chou CK, Chen CY, Hu WH, Tsai MH, Hsu YC, Shun CT, Luo JC, Lin JT, El-Omar EM, Wu MS, Liou JM; Taiwan Gastrointestinal Disease and Helicobacter Consortium
Lancet Gastroenterol Hepatol 2023 Jul;8(7):623-634. Epub 2023 May 10 doi: 10.1016/S2468-1253(23)00097-3. PMID: 37178702
Helicobacter pylori Infection in Pediatric Patients: Update on Diagnosis and Eradication Strategies.
Kotilea K, Kalach N, Homan M, Bontems P
Paediatr Drugs 2018 Aug;20(4):337-351. doi: 10.1007/s40272-018-0296-y. PMID: 29785564
Epidemiology, clinical impacts and current clinical management of Helicobacter pylori infection.
Mitchell H, Katelaris P
Med J Aust 2016 Jun 6;204(10):376-80. doi: 10.5694/mja16.00104. PMID: 27256648
Helicobacter connections.
Marshall B
ChemMedChem 2006 Aug;1(8):783-802. doi: 10.1002/cmdc.200600153. PMID: 16902931

Therapy

Updated joint ESPGHAN/NASPGHAN guidelines for management of Helicobacter pylori infection in children and adolescents (2023).
Homan M, Jones NL, Bontems P, Carroll MW, Czinn SJ, Gold BD, Goodman K, Harris PR, Jerris R, Kalach N, Kori M, Megraud F, Rowland M, Tavares M; on behalf of ESPGHAN/NASPGHAN
J Pediatr Gastroenterol Nutr 2024 Sep;79(3):758-785. Epub 2024 Aug 15 doi: 10.1002/jpn3.12314. PMID: 39148213
Molecular testing-guided therapy versus susceptibility testing-guided therapy in first-line and third-line Helicobacter pylori eradication: two multicentre, open-label, randomised controlled, non-inferiority trials.
Chen MJ, Chen PY, Fang YJ, Bair MJ, Chen CC, Chen CC, Yang TH, Lee JY, Yu CC, Kuo CC, Chiu MC, Chou CK, Chen CY, Hu WH, Tsai MH, Hsu YC, Shun CT, Luo JC, Lin JT, El-Omar EM, Wu MS, Liou JM; Taiwan Gastrointestinal Disease and Helicobacter Consortium
Lancet Gastroenterol Hepatol 2023 Jul;8(7):623-634. Epub 2023 May 10 doi: 10.1016/S2468-1253(23)00097-3. PMID: 37178702
High Effective of 14-Day High-Dose PPI- Bismuth-Containing Quadruple Therapy with Probiotics Supplement for Helicobacter Pylori Eradication: A Double Blinded-Randomized Placebo-Controlled Study.
Poonyam P, Chotivitayatarakorn P, Vilaichone RK
Asian Pac J Cancer Prev 2019 Sep 1;20(9):2859-2864. doi: 10.31557/APJCP.2019.20.9.2859. PMID: 31554388Free PMC Article
Toward population specific and personalized treatment of Helicobacter pylori infection.
Liou JM, Chen PY, Kuo YT, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium
J Biomed Sci 2018 Oct 2;25(1):70. doi: 10.1186/s12929-018-0471-z. PMID: 30285834Free PMC Article
Helicobacter pylori Infection in Pediatric Patients: Update on Diagnosis and Eradication Strategies.
Kotilea K, Kalach N, Homan M, Bontems P
Paediatr Drugs 2018 Aug;20(4):337-351. doi: 10.1007/s40272-018-0296-y. PMID: 29785564

Prognosis

Why the Vonoprazan Helicobacter pylori Therapies in the US-European Trial Produced Unacceptable Cure Rates.
Graham DY
Dig Dis Sci 2023 May;68(5):1691-1697. Epub 2023 Mar 1 doi: 10.1007/s10620-023-07886-5. PMID: 36856926
High Effective of 14-Day High-Dose PPI- Bismuth-Containing Quadruple Therapy with Probiotics Supplement for Helicobacter Pylori Eradication: A Double Blinded-Randomized Placebo-Controlled Study.
Poonyam P, Chotivitayatarakorn P, Vilaichone RK
Asian Pac J Cancer Prev 2019 Sep 1;20(9):2859-2864. doi: 10.31557/APJCP.2019.20.9.2859. PMID: 31554388Free PMC Article
Toward population specific and personalized treatment of Helicobacter pylori infection.
Liou JM, Chen PY, Kuo YT, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium
J Biomed Sci 2018 Oct 2;25(1):70. doi: 10.1186/s12929-018-0471-z. PMID: 30285834Free PMC Article
Helicobacter pylori and Gastric Malignancy.
Fischbach W, Chan AO, Wong BC
Helicobacter 2005;10 Suppl 1:34-9. doi: 10.1111/j.1523-5378.2005.00338.x. PMID: 16178969
Helicobacter pylori infection in pediatrics.
Wewer V, Kalach N
Helicobacter 2003;8 Suppl 1:61-7. doi: 10.1046/j.1523-5378.2003.00165.x. PMID: 14617219

Clinical prediction guides

rs2671655 single nucleotide polymorphism modulates the risk for gastric cancer in Helicobacter pylori-infected individuals: a genome-wide association study in the Korean population.
Shin CM, Park K, Kim N, Won S, Ohn JH, Lee S, Park JH, Kang SJ, Kim JS, Lee DH
Gastric Cancer 2022 May;25(3):573-585. Epub 2022 Mar 24 doi: 10.1007/s10120-022-01285-x. PMID: 35325318Free PMC Article
Helicobacter pylori Infection of Primary Human Monocytes Boosts Subsequent Immune Responses to LPS.
Frauenlob T, Neuper T, Mehinagic M, Dang HH, Boraschi D, Horejs-Hoeck J
Front Immunol 2022;13:847958. Epub 2022 Mar 2 doi: 10.3389/fimmu.2022.847958. PMID: 35309333Free PMC Article
DNA methylation accumulation in gastric mucosa adjacent to cancer after Helicobacter pylori eradication.
Tahara S, Tahara T, Horiguchi N, Kato T, Shinkai Y, Yamashita H, Yamada H, Kawamura T, Terada T, Okubo M, Nagasaka M, Nakagawa Y, Shibata T, Yamada S, Urano M, Tsukamoto T, Kurahashi H, Kuroda M, Ohmiya N
Int J Cancer 2019 Jan 1;144(1):80-88. Epub 2018 Nov 12 doi: 10.1002/ijc.31667. PMID: 29978464
Toward population specific and personalized treatment of Helicobacter pylori infection.
Liou JM, Chen PY, Kuo YT, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium
J Biomed Sci 2018 Oct 2;25(1):70. doi: 10.1186/s12929-018-0471-z. PMID: 30285834Free PMC Article
Systemic cytokine levels and subsequent risk of gastric cancer in Chinese Women.
Wong HL, Rabkin CS, Shu XO, Pfeiffer RM, Cai Q, Ji BT, Yang G, Li HL, Rothman N, Gao YT, Zheng W, Chow WH
Cancer Sci 2011 Oct;102(10):1911-5. Epub 2011 Aug 10 doi: 10.1111/j.1349-7006.2011.02033.x. PMID: 21740481Free PMC Article

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